Michael Broman
Section of Cardiology
Assistant Professor of Medicine
Referring Physician Access Line: 1-877-DOM-2730

Training

DegreeYearInstitutionArea
BA1999University of IowaBiochemistry
PhD2007University of Illinois-ChicagoPharmacology
MD2007University of Illinois College of Medicine 
Residency2009The University of ChicagoInternal Medicne
Fellowship2012The University of ChicagoCardiovascular Disease
Fellowship2013The University of ChicagoClinical Cardiac Electrophysiology

Academic Interests

Dr. Broman’s academic research focus is on the role of developmental transcriptional regulators and other genetic factors in the pathogenesis of atrial fibrillation, a common abnormal heart rhythm affecting a large proportion of the general population. His laboratory utilizes animal models and human tissue studies to address questions regarding the roles of, primarily, the GATA4/FOG-2 axis in atrial fibrillation and cardiac failure.


Clinical Interests

Cardiac Arrhythmias;Heart Failure; Pacemakers/Defibrillators;Cardiovascular Genetics


Representative Publications

  1. Vogel SM, Orrington-Myers J, Broman M, Malik AB. 2006. De novo ICAM-1 synthesis in the mouse lung: model of assessment of protein expression in lungs. Am J Physiol Lung Cell Mol Physiol. 291(3):L496-501. PMID: 16714332
  2. Rangarajan D Nadadur, Michael T Broman, Bastiaan Boukens, Stefan Mazurek, Malou van den Boogaard, Jenna Bekeny, Chih-wei Wu, Min Zhang, James F Martin, Vincent Christoffels, Igor Efimov, Elizabeth M McNally, Christopher R Weber, Ivan P. Moskowitz. A TBX5-PITX2 incoherent feed forward loop modulates atrial rhythm. In Press. Science Translational Medicine 2016
  3. Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC. 2014. FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. Sep 6. S0012-1606(14)00421-7. PMID: 25196150
  4. Osbourne A, Calway T, Broman M, McSharry S, Earley J, Kim GH. 2014. Downregulation of connexin43 by microRNA-130a in cardiomyocytes results in cardiac arrhythmias. J Mol Cell Cardiol. May 10;74C:53-63. PMID: 24819345
  5. Michael T. Broman, Panos Kouklis, Xiaopei Gao, Ramaswamy Ramchandran, Radu F. Neamu, Richard D. Minshall, Asrar B. Malik. 2006. Cdc42 Regulates Adherens Junction Stability and Endothelial Permeability by Inducing Alpha-Catenin Interaction With the Vascular Endothelial Cadherin Complex. Circ. Res.;98:73. PMID: 16322481



More Information

For more information about Dr. Michael Broman publications and research collaborations , please click here