Alfredo Garcia
Section of Emergency Medicine
Assistant Professor of Medicine


B.Sc1999The Ohio State UniversityMicrobiology, Biological Sciences
PhD2006Wright State UniversityNeurophysiology
Post Doctoral Fellowship2009The University of ChicagoNeuroscience and Respiratory Physiology

Academic Interests

Dr. Garcia has a broad research interest in the influence of local neuronal environments on neurodevelopment and the coordination of information among neural networks. His current work is focused on understanding the impact of blood gas homeostasis on (1) central cardio-respiratory control, (2) neurodevelopment and (3) synaptic plasticity. This work has implications for the understanding of the neural basis for autonomic function and cognitive dysfunction in conditions ranging from opioid overdose to epilepsy and sleep apnea.

Representative Publications

  1. Garcia, AJ 3rd, JE Koschnitzky, JM Ramirez. (2013) The physiological determinants of Sudden Infant Death Syndrome. Respir. Physiol. Neurobiol. 189:288-300. PMID23735486
  2. Garcia AJ 3rd, S Zanella, T Dashevskiy, SA Khan, MA Khuu, NR Prabhakar and JM Ramirez. (2016) Chronic intermittent hypoxia alters local respiratory circuit function at the level of the preBötzinger complex. Front Neurosci. 10:4. doi: 10.3389/fnins.2016.00004. PMID26869872; PMC4740384
  3. Anderson TM, AJ Garcia 3rd, NA Baertsch, J Pollak, JC Bloom, AD Wei, KG Rai, JM Ramirez. (2016) A novel excitatory network for the control of breathing. Nature 536:76-80. PMID27462817
  4. Raghuraman S, Garcia AJ 3rd, TM Anderson, VD Twede, KJ Curticea, K Chase, JM Ramirez, BM Olivera, RW. Teichert. (2014) Defining modulatory inputs into CNS neuronal subclasses by functional pharmacological profiling. Proc Natl Acad Sci 111: 6449-54. doi: 10.1073/pnas.1404421111. Epub 2014 Apr 14. PMID24733934
  5. Hodge RD, AJ Garcia 3rd, GE Elsen, BR Nelson, KE, Mussar, SL Reiner, JM Ramirez, RF Hevner. (2013) Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus. J. Neurosci. 33:4165-4180.PMID23447624; PMC3623668

More Information

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