Section of Endocrinology, Diabetes and Metabolism
Professor of Medicine
Associate Director, Endocrinology Fellowship Training Program
Referring Physician Access Line: 1-877-DOM-2730
|BS||1963||University of Illinois||Biology
|MD||1967||The University of Chicago||
|Fellowship||1973||Beth Israel Hospital||Endocrinology & Gastroenterology
Dr. Favus’ work centers on three main areas: the metabolic basis of genetic idiopathic hypercalciuria in calcium oxalate stone formers; the action of vitamin D and parathyroid hormone; and osteoporosis. He has identified increases in intestinal and bone vitamin D receptor content in genetic hypercalciuric kidney stone forming rats, an animal model of human idiopathic hypercalciuria. Bone loss and osteoporosis in patients with idiopathic hypercalciuria and the relation to urine calcium loss is also under investigation.
Osteoporosis and related metabolic bone diseases, parathyroid disorders, and calcium nephrolithiasis.
- Yao, Y., Kathpalia, P., Bushinsky, D.A., Favus, M.J. Hyper-responsiveness of vitamin D receptor gene expression to 1,25-dihydroxyvitamin D3: A new characteristic of genetic hypercalciuric stone-forming rats. J. Clin. Invest., 101:2223-2232,1998.
- Caligiuri, P., Giger, M.L., and M.J. Favus. Multifractal radiographic analysis of osteoporosis. Med. Phys. 21:503-508, 1994.
- Favus, M.J., Mangelsdorf D.J., Tembe, V., Coe, B.J., and Haussler, M.R. Evidence for in vivo up regulation of the intestinal vitamin D receptor during dietary calcium restriction in the rat. J. Clin. Invest. 82:218_224, 1988.
- Coe, F.L., Favus, M.J., Crockett, T., Strauss, A.L., Parks, J.H., Porat, A., Gantt, C.L., and Sherwood, L.M., Effects of low calcium diet on urine calcium excretion, parathyroid function and serum 1,25(OH)2D3 levels in patients with idiopathic hypercalciuria and normal subjects. Am. J. Med. 72:25_32, 1982.
- Favus, M.J., Schneider, A.B., Stachura, M.E., Arnold, J.E., Ryo, U.Y., Pinsky, S.M., Colman, J., Arnold, M.J., and Frohman, L.A., Thyroid cancer occurring as a late consequence of head and neck irradiation: Evaluation of 1056 patients. New Engl. J. Med. 294:1019_1025, 1976