Tamara Vokes
Section of Endocrinology, Diabetes and Metabolism
Professor of Medicine
Medical Director, 150 E. Huron; Director, Adult Endocrine Fellowship Program
Referring Physician Access Line: 1-877-DOM-2730

Training

DegreeYearInstitutionArea
MD1977University of Belgrade 
Residency1982Ravenswood HospitalInternal Medicine
Fellowship1983University of CaliforniaEndocrinology
Fellowship1985The University of ChicagoEndocrinology

Academic Interests

Dr. Vokes has a clinical program that focuses on osteoporosis and other metabolic bone diseases. Patients are referred from within the institution as well from the Chicago metropolitan area and the Midwest. As a result, the fellows rotating through this clinic are exposed to wide range of bone pathology. Dr. Vokes' research interest is also in the area of osteoporosis and metabolic bone disease. In the area of osteoporosis, Dr. Vokes has investigated novel approaches to refining the assessment of fracture risk. Among those, she has pioneered the clinical application of Vertebral Fracture Assessment (VFA) in improving identification of patients with highest fractures risk who may need the most aggressive therapeutic approach. In addition, she has studied the possibility of detecting bone fragility using a new method for non-invasive assessment of bone structure known as Radiographic Texture Analysis (RTA) of bone images. This work is done in collaboration with a medical physicist, Dr. Maryellen Giger and has shown promising results demonstrating the utility of RTA in assessing bone fragility. Finally, Dr. Vokes is examining racial differences in fracture risk particularly in relationship to the effects of glucocorticoids on bone fragility, which may differ between Caucasian and African American subjects. In the area of metabolic bone disease, Dr. Vokes is participating in the multicenter clinical trial using PTH replacement therapy for patients with hypoparathyroidsim, the last hormone deficiency syndrome for which hormone replacement therapy has not been available to date. The results of this trial are very promising and are likely to revolutionize the treatment of this disease.


Clinical Interests

Osteoporosis and metabolic bone diseases


Representative Publications

  1. Vokes, T., Lauderdale, D., Ma, S.L., Chinander, M., Childs, K., Giger, M.:Radiographic Texture Analysis of Densitometric Calcaneal Images - Relationship to Clinical Characteristics and to Bone Fragility. 2010 J Bone Miner Res. Jan;25(1):56-63. PMID: 19594292
  2. Vokes, T.J., Gilen, D.: Using clinical risk factors and bone mineral density to determine who among patients undergoing bone densitometry should have Vertebral Fracture Assessment (VFA). 2010 Osteoporos Int. 21 (12): 2083-2091 PMID: 20306020
  3. Lansdown, D., Bennet, B., Thiel, S., Ahmed, O., Dixon, L., Vokes, T.J.: Prevalence of vertebral fractures on chest radiographs of elderly African American and Caucasian women. Osteoporos Int., in press, PMID: 21060991
  4. Mannstadt, M., Clarke, B., Vokes, T., Brandi, M.L., Ranganath, L., Fraser, W.D., Lakatos, P., Bajnok, L., Garceau, R., Mosekilde, L., Lagast, H., Shoback, D., Bilezikian, J.P.: Efficacy and Safety of Recombinant Human Parathyroid Hormone (1-84) in Hypoparathyroidism (REPLACE: a double-blind placebo-controlled, randomized phase 3 study. The Lancet Diabetes & Endocrinology, 1 (4): 275 - 283, December 2013, doi:10.1016/S2213-8587(13)70106-2, epub 07 October 2013
  5. Chou, S., Vokes, T., Ma, S., Costelo, M., Rosen. H. and Schousboe, J: Simplified criteria for selecting patients for vertebral fracture assessment (VFA). Journal of Clinical Densitometry.J Clin Densitom. 2014 Jul-Sep;17(3):386-91. doi: 10.1016/j.jocd.2013.11.003. Epub 2014 Feb 25.



More Information

For more information about Dr. Tamara Vokes publications and research collaborations , please click here