Dan Nicolae
Section of Genetic Medicine
Professor of Medicine

Training

DegreeYearInstitutionArea
BA1995University of BucharestMathematics
PhD1999The University of ChicagoStatistics

Academic Interests

Dr. Nicolae research falls into three areas: the genetics of complex diseases, with an emphasis on asthma related phenotypes, statistical genetics, and theoretical statistics. The current focus of his genetics research is on developing statistical and computational methods for DNA and RNA sequencing data, on data integration, and on system-level approaches.


Representative Publications

  1. Nicolae DL, Gamazon E, Zhang W, Duan S, Dolan ME, Cox NJ (2010) Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discoveryfrom GWAS". PLoS Genetics, 6(4):e1000888.
  2. King CR, Rathouz PJ and Nicolae DL (2010) An Evolutionary Framework for Association Testing in Resequencing Studies". PLoS Genetics, 6(11):e1001202.
  3. Torgerson DG, Ampleford EJ, Chiu GY, Gauderman WJ, Gignoux CR, Graves PE, Himes BE, Levin AM, Mathias RA, Hancock DB, Baurley J, Eng C, Stern DA, Celedn JC, Rafaels N, Capurso D, Conti DV, Roth LA, Soto-Quiros M, Togias A, Li X, Myers RA, Romieu I, Van den Berg DJ, Hu D, Hansel NN, Hernandez RD, Israel E, Salam MT, Galanter J, Avila PC, Avila L, Rodriquez-Santana JR, Chapela R, Rodriguez-Cintron W, Diette GB, Adkinson NF, Abel RA, Ross KD,Shi M, Faruque WMU, Dunston GM, Watson HR, Mantese VJ, Ezurum SC,Liang L, Ruczinski I, Ford JG, Huntsman S, Chung KF, Vora H, Li X, Calhoun WJ, Castro M, Sierra-Monge JJ, del Rio-Navarro B, Deichmann KA, Heinzmann A, Wenzel SE, Busse WW, Gern JE, Lemanske Jr. RF, Beaty TH, Bleecker ER,Raby BA, Meyers DA, London SJ, Gilliland FD, Burchard EG, Martinez FD,Weiss ST, Williams LK, Barnes KD, Ober C, and Nicolae DL (2011) Meta- analysis of Genome-wide Association Studies of Asthma In Ethnically Diverse North American Populations". Nature Genetics, 43(9):887-892.
  4. Caliskan M, Bochkov YA, Kreiner-Moller E, Bonnelykke K, Stein MM, Du G, Bisgaard H, Jackson DJ, Gern JE, Lemanske RF Jr, Nicolae DL, Ober C (2013) Rhinovirus wheezing illness and genetic risk of childhood-onset asthma". New England Journal of Medicine, 368(15), 1398-1407
  5. Reimherr M and Nicolae DL (2014) A Functional Data Analysis Approach for Genetic Association Studies". The Annals of Applied Statistics, 8(1), 406-429.



More Information

For more information about Dr. Dan Nicolae publications and research collaborations , please click here