Yanchun Li
Section of Gastroenterology
Associate Professor of Medicine


BS1983Wuhan UniversityVirology
MS1986Wuhan UniversityMolecular Virology
PhD1991Kent State UniversityBiochemistry
Fellowship1997Massachusetts General HospitalMedicine
Fellowship1997Harvard Medical SchoolMedicine

Academic Interests

Dr. Li ‘s main research interest is the vitamin D endocrine system. His lab is exploring the functions of vitamin D using molecular, cellular and genetic approaches. Their current research focuses on several areas: 1) vitamin D regulation of the renin-angiotensin system and blood pressure as well as mineral metabolism, including renal handling of calcium, phosphate, sulfate and water; 2) exploring roles of the vitamin D receptor in adipogenesis and lipid metabolism in cells and animals; 3) chemoprevention of vitamin D against colon cancer genesis and development; 4)mechanism of vitamin D receptor regulation of the hair growth cycle.

Representative Publications

  1. Kong J, Li XJ, Gavin D, Jiang Y, Li YC. (2002) Targeted expression of human vitamin D receptor in the skin promotes the initiation of postnatal hair follicular cycle and rescues the alopecia in vitamin D receptor null mice. J. Invest. Dermatol. 118:631-638.
  2. Li YC, Kong J, Wei M, Chen Z-F, Liu SQ, Cao L-P. (2002) 1,25-Dihydroxy-vitamin D3 is a negative endocrine regulator of the renin-angiotensin system. J. Clin. Invest. 110:229-238.
  3. Kong J, Li YC. (2003) Effect of ANG II type I receptor antagonist and ACE inhibitor on vitamin D receptor-null mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 285:R255-R261.
  4. Bolt MJG, Liu W, Qiao G, Kong J, Zheng W, Krausz T, Cs-Szabo G, Sitrin MD, Li YC (2004) Critical role of vitamin D in sulfate homeostasis: Regulation of the sodium-sulfate co-transporter by 1,25-Dihydroxyvitamin D3. Am. J. Physiol. Endocrinol. Metab., 287:E744-E749
  5. Xiang W, Kong J, Chen S, Cao L-P, Qiao G, Zheng W, Liu W, Li X, Gardner DG, Li YC. (2004) Cardiac Hypertrophy in Vitamin D Receptor Knockout Mice: Role of the systemic and cardiac renin-angiotensin systems. Am. J. Physiol. Endocrinol. Metab., in press

More Information

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